One report he cited was published by Jungeblut in 1937. If Vitamin C was given during the incubation stage in monkeys, the subsequent disease was much less severe. But if the disease was in its fifth day, much larger doses of C were required. Even when but 100 mg of C were given in 24 hours to these experimental monkeys, there were six times the number of non-paralytic survivors as in the control group.

Dr. Sabin attempted to discredit the use of Vitamin C in controlling polio in monkeys but did not give enough (100mg), and the monkeys had unmodified poliomyelitis. Scurvy is surely an invitation to infection, but the absence of scurvy does not assure an adequate immune system—especially when an infection invades. Malnutrition plays a definite role in susceptibility to virus infections. “Thousands of children owe their paralyzed limbs to this unfortunate blunder of Sabin.”

He arbitrarily adopted the following routine injection schedule: 1000 to 2000 mg initially depending upon age. The intramuscular route was used for children under age four years. If the fever dropped in two hours, two more hours was allowed before the second dose. After 24 hours, if the fever remained down, this same dose was given every six hours for the next 48 hours. All sixty cases were well in 72 hours. Three however, had a relapse, so the C was continued in all 60 cases for another two days every eight to twelve hours.

Home treatment was 2000 mg injected every six hours plus 1000 to 2000 mg orally every two hours.

Two of the 60 patients had throat muscle paralysis and needed oxygen and drainage but were recovering in 36 hours.

In a follow up article on “The Vitamin and Massage Treatment for Acute Poliomyelitis” (Southern Medicine and Surgery, vol. 114, #8, August, 1952) he summarized his years of treatment of this scourge that hit every summer. He felt much of the fear about the disease was due to reckless propaganda. It is a dramatic disease mainly affecting children. At that time the standard treatment was the splinting of the affected muscles for two to eight weeks to prevent any kind of motion. Surgery was then used to correct contractions and stabilize joints. At about that same time Sister Kenny was urging the use of hot moist packs and early passive motion to relieve spasm. Dr. Klenner used pillows to rest the affected muscles, immediate and continuous massage and passive motion, and, of course, Vitamin C to kill the virus, reduce the swelling in the brain, support the exhausted adrenals and rehabilitate damaged nerve tissue.

Reducing spinal fluid pressure is important to allow nutrients to reach the shocked nerve cells. The edema fluid “pressure in the central nervous system is the end result of the inflammatory reaction caused by the virus.” it is probably augmented by a deficiency of Vitamin B1. Early researchers tried to relieve this pressure by the use of hypertonic sugar (10% dextrose) solutions designed to pull the fluid from the brain, relieving the headache and allowing the circulation to open up sufficiently to permit nutriments into the dying cells. It is known that virus infections deplete the Vitamin C content of the adrenals. Chemical reactions follow resulting in high blood sugar; “apparently the adrenal medulla is released from its inhibiting mechanism allowing a concentration of free adrenaline in the blood high enough to cause vasoconstriction.” Glucose would only serve to aggravate this artificial diabetes (Maybe this is why some children develop diabetes after a virus infection, notably mumps).

Vitamin C works as a destroyer of the virus but also as a safe and potent dehydrator and diuretic. (Most patients complain of thirst after an I.V. of ascorbic acid.) “Given in massive doses it will relieve the edema pressure of the cord and brain, thus allowing normal amounts of B1 to reach chemically shocked nerve cells.” He occasionally used hypertonic sodium lactate as a dehydrator.

Vitamin C is proven to be low in the blood and tissues of virus victims. In a loading test, Heaslip found the urine of virus infected patients only revealed 20% of the ingested dose compared to healthy controls who excreted 44% of the swallowed C.

Jungeblut, a Vitamin C researcher, observed:

   1. If a paralytic dose of polio virus were injected into the brains of monkeys, they all developed paralytic polio. If, however, Vitamin C was injected along with the virus, the animals remained free of the disease.
   2. If monkeys were infected with a high dose of the virus, Vitamin C by injection failed to modify the disease course.
   3. If less virus were given and the Vitamin C was kept at 100 mg per day, the results were variable. Dr. Klenner felt that the virus dose was not standard, and the Vitamin C was too small and too infrequently given.

Dr. Klenner felt the best time to treat the virus was during the viremia stage; that is, when it was floating about in the blood stream and had not invaded the tissues. He repeats: “For optimum results the vitamin must be given in massive doses, every two to four hours, around the clock.” Intestinal absorption is inconsistent; it must be given by needle.

Dr. Klenner wondered if some of the manifestation of polio might be due to mild scurvy. Fever, vomiting, diarrhea, aches are all seen with scurvy and with polio. Certainly when Vitamin C is given all these symptoms and signs disappear. Was it scurvy or polio?

He points out the similarities in pathology in the nerve cells of polio and beri-beri (B1 deficiency). He believed this sequence: the virus causes a Vitamin C deficiency which stresses the medulla of the adrenal gland. Adrenaline is released, which causes not only vascular constriction but affects carbohydrate metabolism, that is, it causes the blood sugar to rise. B1, thiamin, is absolutely necessary for sugar metabolism, and most diets are low in B1. In addition, absorption of vitamins and foods are decreased when a disease is active. The Adrenaline-induced constriction of the blood vessels about the intestines cuts some of the blood supply to the intestinal enzymes. Pyruvic acid accumulates at the neuromuscular junction. To metabolize pyruvates, an enzyme, cocarboxylase, is required. This enzyme has two B1 molecules combined with phosphate; no B1, no action. When pyruvates accumulate at this area, fatigue is the result. The flaccid paralysis of polio is related. B1 therapy is indicated for polio and most cases of fatigue. “Nerve and muscle cells in a flaccid extremity may be only tired, but it is reasonable to believe that unless they are relieved promptly, they may die.” Massage would improve the circulation and help remove toxic agents during this emergency.

In 1956 Dr. Klenner published, “Poliomyelitis—Case Histories” (Tri-State Medical Journal, Sept). He had a continuing supply of zingers he would throw at doctors who insisted on disregarding his logic. He quotes Ratner, “There are two ways of practicing the medical art: the first is to employ art; the second is to employ fancy.” If one has used speculation, preconceived opinions and prejudice, then he is proceeding by emotions, faith and dreams. We must proceed by REASON. Husky put it, “Science commits suicide when it adopts a creed.”

He was disturbed by the enthusiasm preached by the vaccine enthusiasts. They claim that the dead Salk vaccine was safe and that it makes antibodies. He was convinced that was not true. He argued for a live virus, which would be more likely to give the recipients protective antibodies. 98% of all adults possess these antibodies. He seems to be arguing for all of us to acquire a natural immunity to all viral infections by taking enough Vitamin C to attenuate the disease no matter when it strikes.

He suggests for poliomyelitis:

   1. Gentle massage for paralysis, continuous in the first few hours.
   2. Ascorbic acid, best intravenously, at 300 to 500 mg per kg of weight. In small children: two to three grams intramuscularly every two to four hours. Ice on the injected muscle will assuage the pain.
   3. He suggests penicillin and sulfa drugs would be worthwhile, (I would disagree).
   4. Desoxycortisone acetate is suggested daily x 3.
   5. Thiamin, 100 to 250 mg a day for three months will help rehabilitate the nerves.
   6. And make the patient EAT.

He reports some severely ill adults with polio. They had a high fever, 4+ headaches on a scale of one to four, deep eye pain, stilt neck, muscle pain and spasm in the hamstring muscles. Blood tests were negative for bacterial infection.

Injections of twelve to twenty-two grams of Vitamin C were given every twelve hours for six to eight times. The headaches and fever were improved in 48 hours, and most were well in six to ten days at which time oral C was substituted: 1,500 mg or so at three to four hour intervals. Then the B1 for three months to heal the nerves.

Hepatitis

Vitamin C will cure viral hepatitis in two to four days and allow the patient to resume his usual activities. (500-700 mg/kg body weight taken orally; approximately 30 grams/24 hours in orange juice). Dr. Klenner reports that Dr. Bauer at the University Clinic at Basel, Switzerland used just ten grams daily intravenously. It proved to be the best treatment available. He indicated that hepatitis (infectious and serum) can be reversed in a few days using intravenous Vitamin C. Heavy exercise had no effect on the outcome. [Freebern]

1) A 27 year old male with 103° temperature, nausea and jaundice of three days. 60 grams of sodium ascorbate in 600 cc of normal saline was given intravenously at 120 drops/minute. Five grams of Vitamin C was given orally every four hours around the clock. Fifteen grams of C was again given three hours after the first I.V. Another 60 grams of C was given intravenously twelve hours after the initial one (he used 5% glucose in water this time). That one took 75 minutes to accomplish. Then another fifteen grams of C intravenously after two more hours.

For the 30 hours of treatment he received 270 grams intravenously and 45 grams orally—no diarrhea. Temperature was normal at this time and urine clear of bile. Discharged from the hospital, he was back to work. C sets in as a flash oxidizer and helps the body manufacture interferon, a natural antiviral agent.

2) A 22 year old male with chills and fever and a diagnosis of viral hepatitis. His roommate had been admitted the day before. Fifteen grams of sodium ascorbate was given intravenously every twelve hours for three days, then once daily for six days. Sodium ascorbate was swallowed at five grams every four hours (135 grams intravenously, and 180 grams orally). No diarrhea appeared with these doses. He was sent home on the sixth day with no fever and no bile in the urine. Soon he was back to work. His roommate with just bed rest was in the hospital for 26 days!

3) Another male contracted hepatitis in Central America. There, he got lemon juice orally and rectally. Hot mud packs were placed over his liver. He had 104° degree temperature and was sent home. He was told to try bed rest and a protein diet. When Dr. Klenner saw him, he was jaundiced, temperature = 101° and had a very large tender liver. His I.V. was 30 grams sodium ascorbate and one gram calcium gluconate. Oral C: five grams every four hours around the clock for three days. 400 mg adenosine IM. 100,000 units of palmitate Vitamin A given daily. On the fourth day he got 70 grams ascorbate intravenously and one gram calcium. On the sixth day, he got another 70 grams intravenously, and on the seventh day the bilirubin in the serum was down to 1.9 compared to 98 on the first day; SGOT had fallen from 450 to 45. At home he took fifteen grams of C orally, 1,400 mg of choline three times a day plus a high protein and carbohydrate diet—no sequelae.

4) A 42-year-old male suffering from chronic hepatitis had been unsuccessfully treated with steroids for seven months. He was given B complex and Vitamin C: 45 grams of sodium ascorbate plus one gram of calcium gluconate in 500 cc of water with 5% glucose was given intravenously three times a week. He took five grams of C orally every four hours. He was free of the disease in five months. Dr. Klenner felt if he had more massive and continuous doses in the hospital he would have been well in a few weeks, but his peers on the staff would have denied the patient this safe treatment.

Dr. Klenner reemphasized the point, “Sodium ascorbate in amounts ranging up to 900 mg per kilogram body weight every eight to twelve hours will effect cures in two to four days.” Adenosine, 400 to 1,200 mg. intramuscularly, daily.

He felt that the risk of serum hepatitis from dialysis machines could be eliminated by flushing the machines with 50 grams of sodium ascorbate. When he needed to give a patient a blood transfusion he always added ten grams of sodium ascorbate to each pint. The Japanese, he said, have added but five grams of C to each unit of blood; result, no hepatitis and in thousands of cases.
Herpes Simplex & Zoster

Adenosine, 400 mg is given intramuscularly upon diagnosis. Fifteen grams of sodium ascorbate intravenously is next using a six-cc syringe intravenously. Then a second dose of adenosine, 400 mg, 30 minutes after the C. Paint the lesion with tincture of benzoin. Then apply calomine lotion with 5% phenol. Continue to paint only the raw areas, but apply the calomine and phenol to entire area. Continue the injections every twelve hours for three days then daily for several days. A B complex capsule with 100 mg of each of the B’s along with “massive” amounts of Vitamin A orally are taken daily.

To control pain after the lesions heal, a daily I.V. is used containing thiamin, 1000 mg; pyridoxine, 300 mg; niacinamide, 600 mg, diluted to twenty cc with saline, daily for five days. He uses twenty-three gauge, one inch needle.

Herpes simplex must he treated as above for 72 hours as recurrences are common if treatment is shortened.

Fever blisters: three percent ointment of Vitamin C applied to the lips ten to fifteen times a day in a water soluble base speeds up the cure. A three-percent solution of ascorbic acid used as a douche will heal a cervical erosion; direct application of this solution by the physician would be prudent. Twenty grams of C orally each day would “erase this form of malignancy.” Dr. Klenner points out that the cancer seems to hit those with a hereditary tendency; a virus grows more eagerly in the susceptible. If there is a family tendency, oral C in large doses as a preventative makes sense.
Chicken Pox

Vitamin C orally is less reliable. Dr. Klenner noted his own daughter struggling with chicken pox. She was getting 24 grams a day, but papules spread and the itch was intense. After one gram of C intravenously, the itch stopped and she slept well for eight hours. A new I.V. was then given and no new rash appeared. (Untreated chicken pox victims break out for five full days). He noted this ability of C to terminate the usual progress of virus diseases.

One to three injections of 400 mg per kg every eight hours will dry up chicken pox in 24 hours. Controls nausea with one gram of C per five cc of fluid. Thirst is precluded if a glass of juice is drunk just before the I.V.
Hard Measles

He reports some cases:

1. A ten month old baby had the high fever, watery nose, dry cough, the red eyes, and the Koplik spots that gave the disease away: hard measles. He gave 1000 mg of C every four hours. After twelve hours the temperature had fallen to 97.5°; the cough had stopped and the redness of the membranes had cleared. Just to see if this improvement happened to be the natural course of the disease, he stopped the C for just eight hours. The fever rose to 103.4°. The C injections were resumed and the fever dropped in a few hours to 99°. 1000 mg was given every four hours; no rash developed.

II. An eight-year-old developed measles and mumps closely followed by encephalitis (T-104°). He could not eat, was stuporous and responded only to pain. Two hours after one injection of 2000 mg of Vitamin C, he sat up, ate a hearty meal and then played. In six hours he started to revert to his previous stupor, and the fever returned. Twelve hours after a second injection of two grams, and 1000 mg every two hours by mouth, he recovered. Dr. Klenner said, “The rude irritability shown prior to the first injection of Vitamin C was strikingly absent.” I think what he wants the reader to grasp is that the symptoms of these devastating virus diseases are similar to the clues seen in scorbutic patients.

The bloody nose is common in measles, but can be relieved with one or two injections of Vitamin C (one to four grams depending on individual differences). Bleeding tendencies are common with scurvy. Did the disease allow the scurvy to become manifest? These symptoms are due to acute Vitamin C loss and are nature’s way to ask for help.

Mumps

He reports cases of influenza, encephalitis, and measles easily cured with Vitamin C injections and oral doses. A 23-year-old male developed mumps plus bilateral orchitis; his fever was 105°, and he was in overwhelming pain with “testicles the size of tennis balls.” After one 1000-mg injection of Vitamin C intravenously the pain began to subside and after six more shots spaced every two hours the pain was gone. The fever was normal in 36 hours. He was up, about and well in 60 hours. Total dose 25,000 mg.

Mononucleosis

Dr. Klenner felt mono is related to cancer because the same virus (Epstein-Barr) is found in Burkett’s lymphoma. The disease, mono, can be eliminated with an I.V. of C in just a few days, “The actual time being directly proportional to the amount of the vitamin employed in relation to the severity of the infection.” (Most of us use Dr. Cathcart’s formula for the amount of C to be given: “I think this is a 50 gram disease: some fever, generalized aches, but ambulatory.”) In one patient who was given the last rites by her church, the girl’s mother took things into her own hands when the attending physician refused to give ascorbic acid. In each bottle of I.V. fluid she would secretly and quickly “tap in” 20 -30 grams of Vitamin C. The patient made an uneventful recovery. Her mother has her BS in nursing and has been a long time advocate of massive “C” therapy. (100 gram disease: 102-103°, holding down fluids but needs to stay in bed, miserable. 200 gram disease: 104 degree temperature, semi-comatose, somewhat dehydrated; hospitalization a good idea.)

The theory behind the use of adenosine: ascorbic acid stimulates an enzyme which breaks down the nucleic acid in the virus. Some individuals cannot manufacture enough adenosine to aid this enzyme activity. Purines are catabolized and are thus unavailable for the production of new viral nucleic acid.
Other Diseases

Dr. Klenner tells the reader about curing diphtheria with Vitamin C intravenously or intramuscularly. Bacillary dysentery is stopped in 48 hours with injections of C.

Pancreatitis. He treated but one case of this. He put 60 grams of sodium ascorbate in 1000 cc of 5% dextrose in water and let it drip in rapidly and the patient was able to go home in twelve hours.

Cardiovascular diseases, hypermenorrhea, peptic and duodenal ulcers, postoperative and radiation sickness, rheumatic fever, scarlet fever, poliomyelitis, acute and chronic pancreatitis, tularemia, whooping cough, and tuberculosis.

In one case of scarlet fever, antibiotics had no effect, but the fever responded dramatically when 50 grams of C was given intravenously.

Others - Massive doses for rheumatic fever. C will cure TB by removal of the organism’s coat. Also pneumonia—(so it does not matter if one has a viral or bacterial pneumonia, it works).

Rocky Mountain Spotted Fever. Dr. Klenner was an authority in the treatment of this rather debilitating, serious disease because his practice was right in the middle of a constant locus of infection for tick bite fever.

Dr. Klenner had been taught in his training that there was no cure for it, only supportive. So when he was confronted with an obvious case—104.4° degree temperature, spots over body, coma, and positive blood test—he quickly gave 30 grams of C intravenously every six hours. The patient was given para-aminobenzoic acid orally, six grams, every two hours x3, then 4 grams every two hours for 24 hours, then 4 grams every 4 hours until his fever was gone for 24 hours. At about the sixth hour of treatment he became conscious and rational. He was sent home on the sixth day, fully recovered.

He reported the story of a twelve-year-old female with spots and 105° temperature. She was given chloroamphenicol and PABA but with only a poor response on the third day, so she was given an I.V. with 30 grams of C. In two hours she was almost well, cheerful and responsive. She was given 30 grams every eight hours and was well and home in seven days.

He wrote of his son, sick with R.M.S.F. who almost died. He needed Vitamin C, vibramycin (an antibiotic), PABA. Thiamin 1000 mg, B2 300 mg, and B3 500 mg were added to the I.V.’s daily. On the third day his temperature was still up (105 degrees); he was losing interest, and candida was developing. He finally got well on the fourth day.

What Dr. Klenner shows and tells us that with a devastating disease like R.M.S.F.; everything known to be helpful should be used. It seems obvious that antibiotics have a place, but Vitamin C is extremely useful. He pointed out one medical center used the large doses of PABA, and had no fatalities, except a six year old who was given only one half the calculated dose.

The C is given around the clock and at the 500-900 mg per kg body weight level. The disease “can always be reversed.”

Dr. Klenner even treated trichinosis. In the Tri-State Medical Journal for April, 1954, an article entitled, “The Treatment with Massive Doses of Vitamin C and Para-Amino-Benzoic Acid” Dr. Klenner pointed out that sixteen percent of humans in the U.S. have these worms. An acute case will have puffy eyelids, high eosinophil count in the blood stream, pain and swelling of the muscles, fever, profuse sweating, cough and profound weakness. The eosinophil count is high with some allergies also. He found that the lymphocytes stimulate anti-body formation and that the lymphocytes rise with the patient’s recovery.

He reported the case of a man who had eaten sausage. He came down with a fever (104°), very puffy skin of the eyelids, hacking cough. Tests were positive for trichinosis and the eosinophil count was fifteen percent (normal less than four percent).

He was given large doses of C by needle because it would aid antibody formation and to detoxify him. Calcium gluconate, one gram every day for several days. Antibiotics were worthless.

Fever rose to 106°, and he lapsed into a semi-coma. As it reminded Dr. Klenner of tick bite fever, he forced para-aminobenzoic acid down his throat. Four grams initially, then 3 grams every 2 hours. Eight hours after this was started he ate a full breakfast—the first in several days. His profuse sweating stopped. His temperature returned to normal. The PABA was stopped after two days to see the effect; in 36 hours the fever was back up to 101°. The sweating recurred.

The PABA was restarted at three grams every 2 hours during the day and every three hours at night. After 9 days he was well, the PABA was stopped and there was no recurrence.

Another patient, a woman, age 33, had a fever (103.4°), swollen lids, eosinophils 30%, cough. She took 6 grams of PABA and then 3 grams every three hours for 37 hours then that amount every 4 hours. Fruit juice also. Twelve grams of C was given every twelve hours. Ten grams of C orally daily. She returned to work in eight days.

Dr Klenner had no explanation as to why PABA was a curative for trichinosis.

Tetanus (Lockjaw). In two articles in the Tri-State Medical Journal for June and July of 1954, he again scored some points for Vitamin C in “The History of Lockjaw”, and “Recent Discoveries in the Treatment of Lockjaw.”

He stated that lockjaw is not difficult to cure. He believed that doctors rely on antitoxin as the sole therapy because some “authority” recommends it. Many patients are sedated “to the point of narcosis.”

He felt that the practice of injecting the tetanus antitoxin into the tissues near the wound was for medico-legal reasons as it had no benefit and might even be harmful. The antitoxin “cannot travel from the circulation into the nervous system and unless it be injected into the nervous tissue, it is relatively valueless.”

Dr. Klenner reports on other research: Vitamin C inactivates the toxin of tetanus.

He recounted the history of a six-year-old boy who had never had any immunizations and developed tetanus after falling off his pony into some brush. Over a period of three weeks the boy developed increasing muscle tightness, abdominal cramps, inability to smile or open his mouth. Liquids were all he could manage. If stimulated his back would arch so his body was as a bridge resting on heels and back of head.

Dr. Klenner used Tolserol to control the convulsive spasm without sedating the senses unduly (the FDA has taken it off the market; Methocarbamol can be used intravenously with comparable results). The boy was treated with Vitamin C, penicillin, tetanus antitoxin and Tolserol. He spent eighteen (18) days in the hospital, but the use of tetanus antitoxin seemed to aggravate the seizures and required more Vitamin C, sedatives and its use definitely prolonged the hospitalization.

He received 2 to 4 grams of Vitamin C every four to six hours depending upon the symptoms and within one hour he would be calm and free of spasms. The idea was to help the body’s natural detoxifying process. He also developed hives from the TAT or the penicillin and needed Benadryl and Adrenaline for that.

He summarized the treatment of tetanus:

   1. debride and clean any wound thoroughly. (He felt ether was good because it kills most bacteria without destroying tissue.)
   2. 75,000 units antitoxin deep intramuscularly above the wound,
   3. intravenous fluids,
   4. massive doses of Vitamin C intravenously around the clock,
   5. intradermal tetanus toxoid, 0.1 cc for five consecutive days,
   6. intravenous Tolserol—now Methocarbamol. He felt all states should pass legislation requiring tetanus toxoid for all ages.

He felt that the number of fatalities from the disease were equal to the number of those who die from the treatment. He emphasized some principles of treatment 30 to 40 years ago that many of us have forgotten: namely, do no harm, and the body has tremendous restorative powers if the doctor will supply it with the raw materials to promote recovery.

Urethritis: Dr. Klenner points to the study done by Rous in 1971. Only three grams of Vitamin C per day stopped the pain and frequency of urination in just four days. Apparently alkaline urine allows phosphate crystals to form; Vitamin C acidified the urine and the crystals went back into solution.

Chronic cystitis is usually associated with alkaline urine. Germs grow more easily in this alkaline urine. Vitamin C will discourage these bacteria and cut the chance of an ascending infection which might devastate the kidneys (pyelitis). Ten grams of C per day are suggested.

Other Conditions

Antabuse is a chemical used to discourage alcoholics from drinking. Alcohol and Antabuse in the body form acetaldehyde; the person feels awful; weak, headaches even coma as this case illustrates. Dr. Klenner felt he may have been the first to recommend Vitamin C in the control of this chemical reaction. The man was on Antabuse. At one Christmas holiday his “friends” persuaded him to drink with them. Shortly thereafter he was brought to the emergency room where Dr. Klenner happened to be. He was unconscious with BP of 90/60. He suffered from shock (same clinical picture with barbiturate poisoning.) His I.V. was 500 ml of 10% glucose in water with 50 grams of sodium ascorbate. After 30 grams had run in, he awakened, felt well and wanted to go home. He got the whole 50 grams in three hours and was sent home. He also received oxygen by nasal mask.

The company that manufactures Antabuse suggests but one gram intravenously as an antidote calling it “massive.” Dr. Klenner felt that amount was “without value.”

For acute alcoholism Dr. Klenner has given 1000 mg of thiamin intramuscularly every two hours until recovery. Pyridoxine, 500 mg is given every six hours. 40 grams of C intravenously will detoxify the patient.

Arthritis: Vitamin C counteracts the damaging effects of aspirin. C is the number one precursor for collagen formation. If serum levels of C are high, synovial fluid is thinner allowing for easier joint movement. Those taking 15 to 25 grams daily will experience commensurate benefit. Prevention seems prudent. “A person who will take ten to twenty grams of ascorbic acid a day along with other nutrients might very well never develop arthritis.”

Cancer: He cites Schlegel’s (Tulane University) use of ascorbic acid (1.5 grams a day only) in preventing bladder cancer recurrence. “This is the so called wasted Vitamin C.”

He “demonstrated that in the presence of ascorbic acid, carcinogenic metabolites will not develop in the urine. They suggested that spontaneous tumor formation is the result of faulty tryptophan metabolism while urine is retained in the bladder.” Other researchers report that the depletion of mast cells from guinea pig skin was due to ascorbic acid deficiency. It suggests Vitamin C is necessary for the formation and maintenance of mast cells.

Vitamin C will control myelocytic leukemia with 25-30 grams orally daily. “How long must we wait for someone to start continuous ascorbic acid drip for two to three months, giving 100 to 300 grams each day, for various malignant conditions?

Small basal cell epithelioma: 30% Vitamin C ointment.

He cites a disturbing study: particles resembling viruses were found in some breast milk samples of women with breast cancer. Could this help to explain why some cancers seem to be “inherited?” It makes sense that all members of cancer prone families should be taking at least ten grams of C daily.

His protocol for treating cancer is printed here in total, although I do not understand the rationale for some of the ingredients. All of this is designed to kill the cancer cells by shoring up the immune system. He even recognized the therapeutic value for a positive attitude.

   1. Use radioactive cobalt when and where indicated.
   2. Give 45 grams of sodium ascorbate intravenously every twelve hours for one month. Then use 60 to 65 grams in 500 cc of normal saline or 5% dextrose in water for five days a week until a cure is obtained. It usually takes five months.
   3. Each bottle is to contain one gram of calcium gluconate, a cc of some B complex, plus 1,200 mg of thiamin, 300 mg of pyridoxine, and 600 mg of niacinamide.
   4. Oral sodium ascorbate, 5, 10, 20, grams daily. The dose depends upon the bowel tolerance.
   5. Vitamin A palmitate, 50,000 units, daily, orally.
   6. Pantothenic acid, (B5) one gram orally four times a day.
   7. Amino acid protein powder with all the eighteen amino acids. 60 tablets each day or, if a powder, several tablespoons daily. This supports the immune system and the enzymes. Tyrosine should be taken separately, if possible, as this one makes the others work better; 500 mg tablets—six daily.
   8. In addition, a high protein diet using white chicken meat, fresh fish, chicken livers, and brown-shelled eggs. Beef (but once a week) should be as lean as possible: lean stew beef or sirloin tip are the best but have the butcher grind it three times. Hamburgers? Only once a week. No sugar and no starches. Fruit and fruit juices are permitted. Almonds are excellent.
   9. 30 to 40 apricot almonds should be chewed every day in divided doses until a continuous bitter almond taste develops. At this point the patient cuts the dose in half. “This will form cyanide by way of the stomach acid. Cyanide will kill cancer cells. Vitamin C will protect one against the lethal effects of cyanide. It is the antidote. 500 mg tablets of vitamin B17 are available. One after each meal and at bed time.” (Not everyone would agree with this part of the therapy. Cancer victims are still getting amygdalin B17, as injections from Mexico, but there is some doubt as to its efficacy. LHS)
  10. Vitamin E, d-alpha tocopheryl acetate, 400 International unit size, 3,200 units daily. Don’t take iron with it.
  11. One pint of grape juice daily.
  12. B complex tablets with 100 mg of each of the B’s and 100 mcg of B12. Six to eight tablets daily. Theragran-M or a similar capsule with all the minerals to replace what is being pulled out by the C.
  13. Maintain the hemoglobin at 13 grams.
  14. Keep a good attitude.

He reported a case of a man with lymph glands all over his body. He got the above treatment and although the glands increased in size for a while, his liver and spleen were back to normal size in four months. Dr. Klenner noticed a ‘parachute-like’ substance in the urine. Microscopic examination revealed they were clumps of cancer cells.

Another case was that of a woman who had an adenocarcinoma of two years duration. She had had chemotherapy, two surgeries and extensive radiation over her chest, especially the neck area where the cancerous glands were. The cancer had spread to her lungs, her abdomen and six glands in her neck. Dr. Klenner gave her the above protocol. In three months the lesion in her lung had cleared and gone were the glands in her neck. After six months of intravenous Vitamin C and the B complex, the abdominal masses had disappeared, but she could not swallow food. The radiation had scarred her esophagus beyond dilatation and she refused more surgery. The cancer was gone; she died from starvation due to the radiation.

Dr Klenner summarized this paper with this: “The results suggest that larger daily amounts could be given in a hospital with faster results. I would suggest at least 100 grams in 1000 cc of fluid and given every twelve to 24 hours. The vitamins and the calcium gluconate also must be given.” He thought interferon could be assayed while the patient is in the hospital. “How long will it take for the general population to challenge the drug cartel?”

There is a relationship of Vitamin C and cholesterol. Scorbutic guinea pigs have high cholesterol levels. Way back in 1947 high intravenous doses of Vitamin C were found effective in lowering cholesterol levels. One researcher [Spittle, 1971, Lancet] postulated that arteriosclerosis might be the end result of a long term deficiency or negative balance of Vitamin C. [Hecker] He and Dr. Klenner saw the cholesterol levels in the blood of subjects vary with the amount of C used. In one patient the cholesterol was lowered 42 mg percent in six weeks when his oral intake of Vitamin C was increased from 10 grams a day to 20 grams a day.

This all makes sense as “the main pathway of cholesterol catabolism is in conversion to bile salts.” Vitamin C aids in the enzymatic conversion. Guinea pigs, who like humans cannot manufacture their own Vitamin C, will use up dietary Vitamin C if fed a high cholesterol diet. “Guinea Pigs fed a diet free of ascorbic acid showed a 600% acceleration in cholesterol formation in the adrenal glands.” The Soviets have published many articles demonstrating these effects. This might explain why colds and virus flu are more common in the winter because fresh fruits and vegetables are less available and fat in the diet in the winter might use up Vitamin C faster. Gallstones can be made to develop in guinea pigs when fed a diet rich in cholesterol and low in C.

(In Medical School we were given the mnemonic to aid in the diagnosis of the gall stone victims: “Fair, fat, and forty.” Susceptibility plus dietary factors; it makes a lot of sense.)

Dr. Klenner quotes the literature as to the use of Vitamin C in coronary artery disease in animals as well as humans. Arteriosclerosis develops in guinea pigs when fed a high cholesterol diet but develops rapidly in scorbutic animals even without exogenous cholesterol. Extra C was able to absorb the plaques. The diet is important, but extra C seems to be critical especially in those with a family tendency.

“We must protect our hearts from stress. Adequate Vitamin C is one answer.” Where did Linus Pauling learn about his need for large doses? Probably from Dr. Klenner. “Mortality rate for middle-aged people dropped significantly with increased doses of Vitamin C” [Dr. Klenner was quoting J. Stamler from Comprehensive Treatment of Essential Hypertensive Diseases. Monograph on Hypertension, Merck, Sharp and Dohme.] Pauling currently takes 18 grams a day. He seems to be doing well at the age of 86 years (July, 1987). [Dr. Pauling lived to 93 years –ed.]

Cavities: A gram of Vitamin C every day for each year of life (five grams a day for the five year old) will prevent cavities. Ten grams a day from age ten years for a lifetime should maintain that advantage.

He quotes Shaw who felt that deposits on the teeth represent a pre-scurvy condition and that those so afflicted should be taking 2000 mg a day of C before some nasty virus strikes.

Disc, ruptured intervertebral: will be prevented with the ten-grams-a-day dose. Adequate amounts seem necessary for disc metabolism and maintenance.

Corneal ulcers: healed with but 1.5 grams of C daily. The pain of a corneal burn was relieved immediately with twelve grams of C intravenously. The cornea was normal in 24 hours. [Boyd & Campbell]

Diabetes: He noted back in 1951 that the urine in his patients showed a reducing substance; severe virus infections will allow sugar to spill into the urine. Vitamin C acts as a reducing agent and it would appear that diabetes has been induced.

He reported the story of a seven year old diabetic, who developed measles, and his insulin requirements went from 5 units to more than 90 units a day, but with one gram of Vitamin C every four hours his infection and elevated blood sugar came under control. In these diabetic cases, the Vitamin C can be cut back to reasonable levels after the infection is under control. Large prolonged doses of “Vitamin C might prove undesirable due to its dehydrating and diuretic powers.”

He feels that the pathological condition in this case means that adrenaline was flooding the boy’s system. The regulator of the adrenaline mechanism had been removed so the constant supply caused a prolonged vascular constriction. This action on the blood vessels creates asphyxia of the tissues leading to acidosis. This acidity leads to adrenaline hyperglycemia. “Slight blood sugar elevation can be controlled with sodium bicarbonate. This vascular constriction is operative in the pancreas and could restrict the production of insulin and pancreatic enzymes.”

As a matter of fact Dr. Klenner had been studying the effects of ten grams of C per day orally in patients with diabetes mellitus; 60% were able to control the condition with diet and C. The other 40% were able to reduce the insulin dose. Wounds healed more readily. The C assists the liver in its function of carbohydrate metabolism.

Glaucoma: Dr. Klenner was disturbed that marijuana was being used for the reduction of intraocular pressure. ”One would need to be a chain smoker to maintain worthwhile levels.“ He quotes Bietti who used large C doses; Virno’s patients use 35 grams of C (100 mg/kg after meals and bedtime) in divided doses during the 24 hours and this osmotic dehydration of the eyeball was safe and effective. “The size of the dose does make a difference—a real difference.”

Dr. Klenner has found in his investigation of over 300 pregnancies, that the stress of the condition pushed the needs for C in women up to 15 grams a day. The human fetus is a parasite draining available C from the mother. We are all different and our needs for Vitamin C vary depending upon heredity, environment, stress—or its perception. He reminds us of Roger Williams’ research in 1968 showing that some guinea pigs needed twenty times more Vitamin C than others to maintain their health. (The usual dose for pregnant humans: 4 grams daily in the first trimester; 6 grams daily in the second trimester; 8 to 10 grams in the third trimester). He obtained excellent results with these large doses of C in women who had been habitual aborters. [Greenblatt] One woman had had five miscarriages and then with the Vitamin C went on to have two normal pregnancies. The German literature is full of cases of these good results. Hemoglobin was easier to maintain, leg cramps were less (Vitamin C enhances iron and calcium and magnesium absorption). Striae gravidarum (stretch marks) were seldom encountered. Labor was shorter and less painful. No post partum hemorrhage. The perineum was more elastic and if Vitamin C was maintained, it continued to remain firm.

Infants are robust with this Vitamin C. None required resuscitation. 50 mg of ascorbic acid was begun on the infant’s second day and was gradually increased as time went on. A set of quadruplets in this series were healthy and taking milk on the second day. It is especially helpful for the rapidly growing connective tissue, teeth and blood vessels. [King]

Schizophrenia: Dr. Klenner reminds us of Hoffer and Osmond’s work with niacin and Vitamin C back in the early 1950’s. Six to 8 grams of C a day made the niacin work. One schizophrenic took one gram every hour for 48 hours and was completely recovered for six months with no further treatment. These megadoses halved the suicide rate. It has been demonstrated that schizophrenics burn up C ten times faster than the normal population. Most people show some spill of C in the urine at 4 grams per day; schizophrenics have to take ten times this amount before it can be detected. Dr. Klenner noticed this spillage in patients severely affected with a virus only after two to three days of large doses of C and improvement had begun. (Could schizophrenia be due to a virus?)

Burns: can be treated with Vitamin C. “30-100 grams of Vitamin C is the proper amount to employ.” (500 mg per kg of body weight diluted to at least 18 cc per gram of C using 5% dextrose or saline in water or Ringer’s solution, repeated every eight hours for several days, then at twelve hour intervals. Calcium gluconate is added.) “Vitamin C is given until healing takes place.” It takes seven to thirty days depending upon the degree of the burn. It may prevent the need for grafting as it keeps the tissues oxygenated thus preventing the blood from sludging. [Kniseley] On the fourth to fifth day the malodorous burn eschars will fall off leaving normal tissue. Vitamin C also eliminates pain; opiates are less necessary. (It stimulates endorphin production in the brain.)

In an article he published in the ICAN Journal (there is no date, but it was probably published in 1973 or 74) he states that Vitamin C is truly a miracle substance. He believed that large doses of intravenous Vitamin C early in the post-burn phase would eliminate the third degree burn with its infection and scarring. Blood sludging seems to be the basic villain that leads to rigid masses of eschar. [Berkeley] Oxygen is cut off. Tissue destruction is added to already burn-damaged skin. Vitamin C levels in the blood and urine drop. [Lund & Levenson; Lam] Vitamin C is necessary for granulation tissue and skin formation. [Bergman] Three percent ascorbic acid solution is used as a spray every two to four hours for five days. [Klasson]

Pseudomonas: (a nasty bacteria, often seen in burn patients; very resistant to antibiotics): three percent spray plus massive injections.

Heat stroke: 500 mg per kg of body weight will reverse it.

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